DONATE NOW
Get InformedBrain Tumor FactsClinical TrialsNewsVideosSmarter ResearchWhat We FundHow We FundWho We FundScientific GatheringsGet InvolvedWays To GiveJoin An EventPersonal FundraisingAbout UsOur StoryOur TeamOur PartnersTHROUGH OUR EYES Low Grade Glioma Research Workshop Article | February 01, 2013In partnership with UCSF and MD Anderson, Accelerate Brain Cancer Cure brought together researchers from leading medical centers and biotech companies to strategize new therapeutic paths to treat Low Grade Gliomas.? The January research workshop, which was held in San Francisco, focused on understanding the underlying biology of brain tumors such as oligodendrogliomas and astrocytomas.
A primary area of focus at the meeting was around identifying key genetic mutations such as IDH, which might present an opportunity for a therapeutic intervention.? IDH mutations are found in about 70% of lower grade brain tumors and are thought to play a role in cancer metabolism. The research group discussed the potential of inhibiting IDH as a way to slow the progression of tumors where the gene alteration is present.
Beyond the development of specific drugs to treat low grade gliomas, the workshop explored the unique challenges of designing clinical trials for glioma.? The use of imaging as a means to determine if a drug is efficacious was one promising technology platform featured at the workshop.? With newer more refined imaging capabilities, oncologists might be able to see changes at the cellular level and indications of response as patients are given a particular drug.
The research workshop included participation from UCSF, MD Anderson, Memorial Sloan Kettering, Vancouver General Hospital, Massachusetts General Hospital, Johns Hopkins, UCLA, Novartis, Agios, and others.
The complete agenda for the meeting can be viewed here.
Newsletter Issue:?February 2013 Share| More News April 2, 2013 10:00 AM White House Announces BRAIN Initiative The BRAIN Initiative Challenges Researchers to Unlock Mysteries of Human Mind.
February 20, 2013 02:32 PM Improving The Lives Of Those Affected By Brain Tumors Ashley Varner guest blogs about her social work pilot study on the lived experience of family members who live with someone diagnosed with a primary malignant brain tumor. 
January 31, 2013 08:48 PM ABC2-Funded Research Featured in Scientific American The collaboration between academic and industry researchers aims to develop a test to detect genetic brain tumor mutations in cerebral spinal fluid and blood.??? Join us in our fight for a cure! This form needs Javascript to display, which your browser doesn't support. Sign up here insteadTo sign up to receive our emails, fill in the following fields and hit submit. Thanks, and welcome!first namelast name* email* required ? Links HomeDonateGet InformedSmarter ResearchGet InvolvedAbout us Get Involved DonateWays to GiveJoin an EventPersonal Fundraising Twitter Connect With Us Contact UsGet in touch with usFacebookMeet new friends and join the discussion in FacebookTwitterTweet and follow us. News, press & infoRSS Feeds Subscribe to News Copyright 2011 ABC2 All Rights Reserved.Privacy Policy 
I appreciate all of the information that you have shared. Thank you for the hard work!
ReplyDeleteA glioma is a type of tumor that starts in the brain or spine. Gliomas arise from glial cells, which act as a supportive cell in the central nervous system. Gliomas are the second most common type of tumor after meningiomas.