DM

Showing posts with label Finds. Show all posts
Showing posts with label Finds. Show all posts

Tuesday, July 23, 2013

Widowed in Their 20s, Couple Finds Love Again

When Jordan Rice saw Jessica Moreland's wedding photo posted to her blog, "One Day at a Time," he was moved not only by her "raw, wild smile" but the tragedy she had endured.

Jessica's husband Jarronn was killed in a motorcycle accident in 2009, just two and a half months after their wedding.

Jordan, too, had been widowed in his 20s and also blogged. He lost his wife Danielle to a rare heart sarcoma in 2011, a little more than two years after they were married.

Mutual friends suggested Jordan, a lawyer turned New York City pastor, and Jessica, a marketing specialist from Washington, D.C., meet because both had shared overwhelming grief at such a young age.

"Jordan and I talked about this the first time we met -- never feeling like we could be excited about a person again," said Jessica, now 30.

"We knew we would meet someone, but it would never be the same, and nothing could reach the pinnacle that it was before."

But on June 22, they married in a simple ceremony in Baltimore that friends say even included the families of their late spouses and brought all to tears.

"There wasn't a dry eye in the room, even the waiters," said the bride, who is now 30 and Jessica Rice.

"I liken it to being a parent," she told ABCNews.com. "You love a child to death, but when you have a second child, you don't love them less."

The couple left this week for a honeymoon in Italy, but the video of their story, which was shown at their wedding, has gone viral with nearly 18,000 views.

"This story could have been scripted for a Lifetime movie," said Jordan's best friend of 13 years, Justin Jones-Fosu, who is in theological school in Mississippi. "They are handsome, beautiful, intelligent, quirky -- but their relationship is really awesome.

"The fact that God could bring them together is almost too good to be true."

Jessica met her husband Jarronn in 2004 when they both worked at Johnson & Johnson in New Jersey. They married in 2009 and relocated to the Maryland area.

"We were everything I could imagine as soul mates," she said.

But just months after they married, Jarronn went on a short motorcycle ride with friends and ended up in intensive care, fighting for his life.

"His injuries were so serious that the blood had drained out of his body," said Jessica. "There was too much strain on his heart."

She was widowed for three years and dated others.

"One guy was great, but it was always really challenging for him to understand my history, and I think he really struggled with the idea that I could expand to love someone else," Jessica said.

Meanwhile, Jordan, now 31, who grew up in New Rochelle, N.Y., met Danielle, a math teacher, and married her in 2009. "For the first six months, it was marital bliss, very much the honeymoon phase," he said.

Soon she began to feel ill, and the couple thought she might be pregnant. An X-ray later revealed Danielle had fluid around her heart that appeared to be a virus.

"She started really getting worse very quickly," said Jordan. "Within four days, she couldn't walk anymore. Her resting heart rate was around 140 beats a minute -- lying down."

Surgeons removed the pressure from around Danielle's heart, but five days later, while sleeping in the hospital waiting room, Jordan was awakened to startling news: Danielle had a rare and deadly form of cancer, primary cardiac angiosarcoma. She died 10 months later.

"I was miserable," he said. "I felt out of place … a 27-year-old doesn't die of cancer. It was very unfair and challenging on every front."

Jordan eventually dated, but said, "I thought I might meet someone cool and nice and sweet, but I don't know if I would be madly in love with this person and feel deeply for them."

In 2012, Jordan's friends were in New York and mentioned a girl, "Jessica," who had also lost her spouse. Like Jordan, they said she was a blogger and had written about her experience.

You are using an outdated version of Internet Explorer. Please click here to upgrade your browser in order to comment.

View the original article here

Wednesday, July 10, 2013

Men Who Can't Produce Sperm Face Increased Cancer Risk, Stanford-Led Study Finds

Main Category: Fertility
Also Included In: Men's Health;??Cancer / Oncology
Article Date: 25 Jun 2013 - 0:00 PDT Current ratings for:
Men Who Can't Produce Sperm Face Increased Cancer Risk, Stanford-Led Study Finds
not yet ratednot yet rated
Men who are diagnosed as azoospermic - infertile because of an absence of sperm in their ejaculate - are more prone to developing cancer than the general population, a study led by a Stanford University School of Medicine urologist has found. And a diagnosis of azoospermia before age 30 carries an eight-fold cancer risk, the study says.

"An azoospermic man's risk for developing cancer is similar to that for a typical man 10 years older," said Michael Eisenberg, MD, PhD, assistant professor of urology at the medical school and director of male reproductive medicine and surgery at Stanford Hospital & Clinics. Eisenberg is lead author of the study, which will be published online June 20 in Fertility and Sterility.

Diagnoses of male infertility and azoospermia are surprisingly common in the United States. About 4 million American men - 15 percent of those ages 15-45 - are infertile. Of these, some 600,000 - about 1 percent of those of reproductive age - are azoospermic. "There is evidence that infertility may be a barometer for men's overall health," Eisenberg said, "and a few studies have found an association of male infertility with testicular cancer." The new study, he said, not only assigns the bulk of infertile men's increased cancer risk to those with azoospermia, but also suggests that this risk extends beyond testicular cancer.

Eisenberg conducted most of the analysis for the study at Stanford, using data gathered from the Texas Cancer Registry and the Baylor College of Medicine in Houston, where he completed his medical training. The study's senior authors are Larry Lipshultz, MD, and Dolores Lamb, PhD, professors of urology at Baylor.

The study population consisted of 2,238 infertile men who were seen at a Baylor andrology clinic from 1989 to 2009. Their median age was 35.7 when they were first evaluated for the cause of their infertility. Of those men, 451 had azoospermia, and 1,787 did not. There were otherwise no apparent initial differences between the two groups.

Azoospermia can arise for two reasons. Obstructive azoospermia is caused by a blockage that prevents otherwise plentiful, fit sperm produced in the testes from reaching the ejaculate. But a screen of about one-fourth of the azoospermic men in the study population indicated that the vast majority suffered from the non-obstructive variety: Their testes didn't produce enough sperm for any to reach their ejaculate, most likely because of genetic deficiencies of one sort or another. Fully one-fourth of all the genes in the human genome play some role in reproduction, Eisenberg noted, so there are a lot of ways for the capacity to sire offspring to go astray.

After undergoing a semen analysis, the men were followed for an average of 6.7 years to see which of them turned up in the Texas Cancer Registry. (Fortunately for the analysis, most people tend to stay in the state where they've grown up, said Eisenberg.) Their rates of diagnosed cancer incidence were then compared with age-adjusted cancer-diagnosis statistics of Texas men in general.

In all, a total of 29 of the 2,238 infertile men developed cancer over a 5.8-year average period from their semen analysis to their cancer diagnosis. This contrasted with an expected 16.7 cases, on an age-adjusted basis, for the male Texas population in general (which, Eisenberg said, closely reflects cancer incidence rates for the entire U.S. population). This meant that infertile men were 1.7 times as likely to develop cancer as men in the general population. This is considered a moderately increased risk.

But comparing the cancer risk of azoospermic and nonazoospermic infertile men revealed a major disparity: The azoospermic men were at a substantially elevated risk - nearly three times as likely to receive a diagnosis of cancer as men in the overall population. Infertile men who weren't azoospermic, in contrast, exhibited a statistically insignificant increased cancer risk of only 1.4 times that of men in the overall population.

By excluding men whose cancer diagnosis came within two or three years of their infertility evaluation, the researchers were able to rule out the possibility that azoospermia caused by an undiagnosed cancer had affected the statistics.

While the study wasn't large enough to delineate which specific types of cancer pushed azoospermic men's incidence rates up, the diagnoses they received covered a wide range of cancers: brain, prostate and stomach tumors, as well as melanoma, lymphoma, testicular cancer and cancer of the small intestine. The findings suggest that genetic defects that result in azoospermia may also broadly increase a man's vulnerability to cancer, Eisenberg said, supporting the notion that azoospermia and cancer vulnerability may share common genetic causes.

The study, which was funded by the National Institute for Child Health and Human Development, is the first to examine the cancer risk of azoospermia in particular, or to link it to non-germ-cell cancers. Previous studies have failed to consistently identify any increased risk for nontesticular cancers in infertile men, whether azoospermic or otherwise. In those previous studies, however, azoospermic men couldn't be separately examined because sperm analyses weren't available.

Most striking of all, said Eisenberg, was the cancer risk among azoospermic men who first had their semen analyzed before age 30. They were more than eight times as likely to subsequently develop cancer than Texas males in the general population of the same age. In contrast, there was no relationship between age of semen analysis and risk of cancer for nonazoospermic men.

The good news, Eisenberg said, is that while the cancer risk among young azoospermic men was quite large compared to their same-age peers, their relative youth means that their absolute risk of contracting cancer during the follow-up period remained small. The bad news, he said, is that men in their 30s often don't have a primary health-care provider. He advised that young men who are diagnosed as azoospermic should be aware of their heightened risk and make sure to get periodic checkups with that in mind.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our fertility section for the latest news on this subject. Please use one of the following formats to cite this article in your essay, paper or report:

MLA

Stanford University Medical Center. "Men Who Can't Produce Sperm Face Increased Cancer Risk, Stanford-Led Study Finds." Medical News Today. MediLexicon, Intl., 25 Jun. 2013. Web.
25 Jun. 2013. APA

Please note: If no author information is provided, the source is cited instead.


'Men Who Can't Produce Sperm Face Increased Cancer Risk, Stanford-Led Study Finds'

Please note that we publish your name, but we do not publish your email address. It is only used to let you know when your message is published. We do not use it for any other purpose. Please see our privacy policy for more information.

If you write about specific medications or operations, please do not name health care professionals by name.

All opinions are moderated before being included (to stop spam)

Contact Our News Editors

For any corrections of factual information, or to contact the editors please use our feedback form.

Please send any medical news or health news press releases to:

Note: Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. For more information, please read our terms and conditions.



View the original article here

Wednesday, June 12, 2013

Study Finds Bladder Cancer Recurrence And Mortality Could Improve With Better Treatment Compliance

Main Category: Cancer / Oncology
Also Included In: Urology / Nephrology;??Compliance
Article Date: 05 Jun 2013 - 0:00 PDT Current ratings for:
Study Finds Bladder Cancer Recurrence And Mortality Could Improve With Better Treatment Compliance
1 starnot yet rated
Researchers at UCLA's Jonsson Comprehensive Cancer Center led by Dr. Karim Chamie, assistant professor-in-residence in the department of urology, have found that the burden of bladder cancer on the population is very high, and that more intense surveillance and treatment in the first two years after diagnosis could reduce the number of patients whose cancer returns after treatment and lower the death rate from this disease. The study was published online ahead of press today in the journal Cancer.

Based on their previous research showing underutilization of care for patients with bladder cancer, this is the first study to examine the natural history of the disease from a population standpoint. To date no one has examined the morbidity of recurrence of disease in the US. Chamie and colleagues found that nearly three quarters of patients with high-grade, non-muscle-invasive bladder cancer will suffer return of the disease (recurrence) within 10 years. Thirty-three percent of patients will have their cancers progress to a more advanced form requiring removal of their bladder, radiation therapy, or systemic chemotherapy. An additional 41% will recur without further spread of the disease (progression).

"Even though 80% of bladder cancer patients don't die of their disease within 5 years, most patients will either die of other causes or bladder cancer, require aggressive treatment (removal of the bladder, radiation, and/or chemotherapy), or have recurrence of their disease. What this study hopes to do is highlight the need to comply with treatment guidelines--prevent recurrences by instilling anticancer agents inside the bladder (intravesical) and follow patients more closely within the first two years of diagnosis," said Chamie.

The study was based on a nationwide sample of Medicare Beneficiaries who had high-grade, non-muscle-invasive bladder cancer. "We have level-one evidence that demonstrates that a single instillation of chemotherapy into the bladder can minimize recurrences, and that six instillations can minimize recurrence and progression," Chamie stated further, "Efforts should be increased to offer patients intravesical therapy with the goal of minimizing the burden of this disease."

The researchers also found that the elderly, women, and African-American patients had higher likelihood of dying of bladder cancer than younger patients, men, and whites, respectively.

This study was supported by the American Cancer Society, Ruth L. Kirschstein National Research Service Award Extramural, Jonsson Comprehensive Cancer Center, National Institutes of Health, and National Institute of Diabetes and Digestive and Kidney Diseases.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our cancer / oncology section for the latest news on this subject. Please use one of the following formats to cite this article in your essay, paper or report:

MLA

UCLA. "Study Finds Bladder Cancer Recurrence And Mortality Could Improve With Better Treatment Compliance." Medical News Today. MediLexicon, Intl., 5 Jun. 2013. Web.
5 Jun. 2013. APA

Please note: If no author information is provided, the source is cited instead.


'Study Finds Bladder Cancer Recurrence And Mortality Could Improve With Better Treatment Compliance'

Please note that we publish your name, but we do not publish your email address. It is only used to let you know when your message is published. We do not use it for any other purpose. Please see our privacy policy for more information.

If you write about specific medications or operations, please do not name health care professionals by name.

All opinions are moderated before being included (to stop spam)

Contact Our News Editors

For any corrections of factual information, or to contact the editors please use our feedback form.

Please send any medical news or health news press releases to:

Note: Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. For more information, please read our terms and conditions.



View the original article here