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Showing posts with label Factors. Show all posts
Showing posts with label Factors. Show all posts

Tuesday, July 16, 2013

Four Significant Factors About Cancer of The Colorectal System

Don't take light, as there is nothing crazy about a illness that kills more than 50,000 People annually despite the fact that it is avoidable with analysis,but only about 64 % of Americans are up to date on examining, and even less Nevadans. In 2010, Nevada ranked 46th in being up to date in colon cancer screening among the 50 states and 47th in mortality from this disease.

Here are four significant factors about cancer of the colorectal system analyzing that everyone should take note of:

The first is to know that you have a choice other than colonoscopy for analyzing. Although a colonoscopy every 10 decades is the suggested choice for avoiding cancer of the stomach , a second appropriate choice is a annually waste FIT that assessments for occult blood. This $15-20 assess properly secured with insurance coverage and done in the privacy of your own house will identify 85 % colon cancers, hopefully at an beginning curable stage. Too many People basically will not have a colonoscopy. Although a colonoscopy is suggested, a stool FIT is far better than doing nothing and joining the ranks of the 50,000.The second is to know the importance of a family history. If anyone has a origins of cancer of the colon in a mom or dad, kid or sibling, particularly if that cancer happened before the age of 60, the chances of cancer of the colon can be 3-4 times higher than normal. Examining then should begin 10 decades before age of the youngest family member with cancer, or age 40, whatever is very first. Moreover, if that relative's cancer happened before age 60, analyzing should be done every five decades instead of 10.The third is the importance of a thorough bowel planning. Do not worry about it. Every colonoscopy needs a cleaning of the stomach to let recognition and removal of any little polyps present that could later become a cancerous. This cleansing is as essential as the process itself. Today's polyp hidden by a poor preparation, can be tomorrow's cancer.Bowel preparation are much more appropriate than they use to be. The amounts are decreased by 50 %, and the flavor is more delightful. Cleaning is best and the planning is better accepted if it is divided in sections, 50 % taken the night before and the other five hours before the process. Getting the preparation efficiently can be challenging, but the attempt can secure your lifestyle.It all is to talk about with your family about the value of analyzing. Each Valentine's Day, consider whether you and your loved ones are up to date in colon cancer screening. There is nothing more satisfying than a couple's colonoscopy during Colon Cancer Awareness Month.Vaileria is a professional editor and writer for more than two decades, published in national and regional newspapers and magazines.I have done master's degree in health journalism and has written extensively about colon health, colon nutrition , colon cancer, colon treatment, colon cancer screening , personal finance and other consumer topics. Rate this Article

Four Significant Factors About Cancer of The Colorectal SystemRating: 5.0/5 (1 vote cast)

Vaileria Sed has published 3 articles. Article submitted on March 28, 2013. Word count: 453

A recent study concluded that environmental factors were the initiating event in the majority of cancers. The strongest contender for the cause of cardiovascular disease, breast cancer, leukaemia, diabetes and suicide is artificial electromagnetic radiation - "dirty electricity".

Written by: Donna M Fisher

Smoking Gets Worse for You the Longer You Do It. From Higher Cancer Risks to Increased Difficulty Breathing, the Effects Are Cumulative.

Written by: Nathan Roberson

One of the most common health problems is indigestion, which primarily affects the digestive system. In fact, any doctor can tell you that stomach pains are one of the more frequent digestive problems facing people today.

Written by: Stefania Constantin

Mesothelioma the medical name for cancer of the lung or the abdomen lining, and is usually caused by exposure to asbestos. Typically, the symptoms of mesothelioma occur after twenty to fifty years of asbestos exposure.

Written by: Samee Ullah


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Wednesday, June 19, 2013

4 New Genetic Risk Factors Identified For Testicular Cancer

Main Category: Cancer / Oncology
Also Included In: Men's Health;??Genetics
Article Date: 14 May 2013 - 1:00 PDT Current ratings for:
4 New Genetic Risk Factors Identified For Testicular Cancer
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A new study looking at the genomes of more than 13,000 men identified four new genetic variants associated with an increased risk of testicular cancer, the most commonly diagnosed type in young men today. The findings from this first-of-its-kind meta-analysis were reported online in Nature Genetics by researchers at the Perelman School of Medicine at the University of Pennsylvania.

The discovery of these genetic variations - chromosomal "typos," so to speak - could ultimately help researchers better understand which men are at high risk and allow for early detection or prevention of the disease.

"As we continue to cast a wider net, we identify additional genetic risk factors, which point to new mechanisms for disease," said Katherine L. Nathanson, MD, associate professor in the division of Translational Medicine and Human Genetics within the department of Medicine. "Certain chromosomal regions, what we call loci, are tied into testicular cancer susceptibility, and represent a promising path to stratifying patients into risk groups - for a disease we know is highly heritable."

Tapping into three genome-wide association studies (GWAS), the researchers, including Peter A. Kanetsky, PhD, MPH, an associate professor in the department of Biostatistics and Epidemiology, analyzed 931 affected individuals and 1,975 controls and confirmed the results in an additional 3,211 men with cancer and 7,591 controls. The meta-analysis revealed that testicular germ cell tumor (TGCT) risk was significantly associated with markers at four loci - 4q22, 7q22, 16q22.3, and 17q22, none of which have been identified in other cancers. Additionally, these loci pose a higher risk than the vast majority of other loci identified for some common cancers, such as breast and prostate.

This brings the number of genomic regions associated with testicular cancer up to 17 - including eight new ones reported in another study in this issue of Nature Genetics.

Testicular cancer is relatively rare; however, incidence rates have doubled in the past 40 years. It is also highly heritable. If a man has a father or son with testicular cancer, he has a four-to six-fold higher risk of developing it compared to a man with no family history. That increases to an eight-to 10-fold higher risk if the man has a brother with testicular cancer.

Given this, researchers continue to investigate genetic variants and their association with cancer.

In 2009, Dr. Nathanson and colleagues uncovered variation around two genes - KITLG and SPRY4 - found to be associated with an increased risk of testicular cancer. The two variants were the first striking genetic risk factors found for this disease at the time. Since then, several more variants have been discovered, but only through single GWAS studies.

"This analysis is the first to bring several groups of data together to identify loci associated with disease," said Dr. Nathanson, "and represent the power of combining multiple GWAS to better identify genetic risk factors that failed to reach genome-wide significance in single studies."

The team also explains how the variants associated with increased cancer risk are the same genes associated with chromosomal segregation. The variants are also found near genes important for germ cell development. These data strongly supports the notion that testicular cancer is a disorder of germ cell development and maturation.

"TGCT is unique in that many of the loci are very good biological candidates due to their role in male germ cell development," said Dr. Nathanson. "Disruptions in male germ cell development lead to tumorigenesis, and presumably also to infertility. These conditions have been linked before, epidemiologically, and genes implicated in both of our prior studies, but this study reinforces that connection."

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our cancer / oncology section for the latest news on this subject. This study was supported in part by Intramural Research Program of the National Cancer Institute and the National Institutes of Health grant (R01CA114478).
University of Pennsylvania School of Medicine Please use one of the following formats to cite this article in your essay, paper or report:

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