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Showing posts with label Throat. Show all posts
Showing posts with label Throat. Show all posts

Friday, July 5, 2013

HPV Throat Cancer on Rise

Oral cancers like the one actor Michael Douglas referenced in a recent newspaper interview are on the rise in the United States, and doctors say that about 10,000 cases a year could be prevented with safe and effective vaccines.

The star of HBO's "Behind the Candelabra" spoke about his throat cancer that was diagnosed in 2010 and its sometime association with the ubiquitous human papillomavirus, or HPV, and oral sex.

"Because without wanting to get too specific, this particular cancer is caused by HPV [human papillomavirus], which actually comes about from cunnilingus," today's edition of The Guardian newspaper quoted the 68-year-old actor as saying.

Oral sex is being linked to rise in throat cancers.

But the actor's publicist, Allen Burry, told ABCNews.com today that his client "never said it was the cause of his particular cancer. They did discuss it. He did say oral sex is a suspected cause of certain oral cancers. He did not say it was his specifically."

About 63 percent of the estimated 11,726 cases of oropharyngeal cancers diagnosed each year in the United States are thought to be caused by HPV, according to the Centers for Disease Control and Prevention. Another 3,000 Americans are diagnosed each year with HPV-associated anal cancer and the rate of infection appears to be increasing.

"Right now in the United States only 2 percent of boys are vaccinated, which is shocking because by the time they are adults, these boys will be more likely to get cancer from HPV than girls," said Dr. Kevin Cullen, director of the University of Maryland's Marlene and Stewart Greenebaum Cancer Center.

"By the time they become adults, throat cancer from HPV in men is four times more likely than cervical cancer in women."

Throat cancer resources are available from experts.

HPV spreads via oral, vaginal and anal intimacy, as well as through cunnilingus and fellatio. The virus does not live in the blood, semen or vaginal secretions. It takes about 20 years for exposure to the virus to develop into cancer.

Doctors say that changing sexual behaviors -- earlier sex, more partners and especially oral sex -- are contributing to a new epidemic of orpharyngeal squamous cell cancers, those of the throat, tonsils and base of the tongue.

Similarly high rates have also been seen in Europe, where a 2010 Swedish study showed a strong correlation between oral cancers and oral sex.

About 50 percent of all girls are vaccinated against HPV-related cervical cancer, a number which is slowly increasing because of strong CDC recommendations, Dr. Cullen said. Women do get HPV-related throat cancer, but at a much lower rate than men.

"The take home message is this virus is out there and virtually everyone is exposed as they become sexually active ... no matter what point in life," he said. "And boys are at greater risk than girls."

The CDC recommends two licensed vaccines, Gardasil and Cervarix, to protect against cervical, anal and oral cancers, but those guidelines have never been fully embraced by parents or young adults.

"Why not prevent what's preventable? HPV infects both sexes," Austin, Texas, pediatrician Dr. Ari Brown said. "And, while the biggest benefit for boys to get this shot is prevention against spreading it to girls, boys are at risk for other types of HPV-related cancers as well as genital warts."

But even as HPV-related head, neck and throat cancers are on the rise -- by more than 225 percent between 1988 and 2004, according to one study in the Journal of Clinical Oncology -- vaccination rates remain low.

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Saturday, June 15, 2013

Can Oral Sex Cause Throat Cancer?

Editor's Choice
Main Category: Ear, Nose and Throat
Also Included In: Cancer / Oncology;??Sexual Health / STDs;??Public Health
Article Date: 04 Jun 2013 - 11:00 PDT Current ratings for:
Can Oral Sex Cause Throat Cancer?
5 stars4 and a half stars
Michael Douglas was diagnosed with throat cancer (oropharyngeal cancer) three years ago. He initially said it was caused by years of heavy smoking, alcohol abuse and stress. However, he recently told The Guardian newspaper that it was caused by oral sex (cunnilingus).

In an Interview with Guardian reporter, Xan Brooks, Douglas said that his type of cancer was caused by the human papillomavirus (HPV) "which actually comes from cunnilingus". His agent later said Douglas had been talking generally, and not about his own cancer, but the Guardian responded by publishing the sound recording of the interview that clearly showed he blamed oral sex for his cancer, and not years of drinking, smoking and stress.

Douglas first revealed details of his throat cancer in the David Letterman Show, in September 2010.

Gypsyamber D'Souza, PhD, MPH, from the Johns Hopkins School of Public Health, and team explained at the American Society of Clinical Oncology (ASCO) annual meeting in Chicago, Illinois, that throat cancers that arise from HPV do not appear to raise the risk for domestic partners of the same cancer.

Dr. D'Souza explained that in their pilot study, they found that the prevalence of HPV among partners/spouses of an affected patient was approximately 7%, no different from that of the general population.

The team found that the HPV 16 subtype was present in just 2% of female partners and 0% of male partners. HPV 16 is responsible for the majority of throat cancers. Of the partners/spouses who underwent a visual oral exam, none had cancer or pre-cancer.

D'Souza explained that the risk of developing head and neck cancers for people whose partners have HPV-related cancer is very low.

At a press briefing, D'Souza said "Many people become infected but are able to clear those infections."

The researchers added that partners who have been together for a long time probably already share whatever infections they have. No changes in physical intimacy are needed, they emphasized. Put more simply "Couples will infect each other with whatever they have anyway - oral sex will neither increase nor reduce infection risk".

In a study published in NEJM (New England Journal of Medicine), Dr Maura Gillison of Johns Hopkins Bloomberg School of Public Health in Baltimore, Maryland, USA, and team suggested that people who have oral sex with at least 6 different partners have a significantly higher risk of developing throat cancer.

The team recruited 100 patients who had recently been diagnosed with oropharyngeal cancer, as well as 200 "healthy" individuals (the control group).

They found that people who had at least 6 oral-sex partners during their lifetime were 3.4 times more likely to have throat cancer. Those with 26 or more vaginal-sex partners had a 3.1 times higher risk of developing throat cancer.

Smoking - this is by far the most important risk factor for throat cancer. Regular, long-term, heavy smokers are 20 times more likely to develop some type of throat cancer compared to non-smokers.

Alcohol - heavy, chronic alcohol consumption, particularly spirits, also raises the risk of developing throat cancer.

People who do both - drink and smoke a lot - have the highest risk.

Frequent heartburn - non-drinkers and non-smokers who have frequent heartburn have a higher risk of developing cancers of the throat and vocal cord.

Written by Christian Nordqvist
Copyright: Medical News Today
Not to be reproduced without permission of Medical News Today

Visit our ear, nose and throat section for the latest news on this subject. "Oral HPV infection in HPV-positive oropharyngeal cancer cases and their spouses"
Gypsyamber D'Souza, Neil D. Gross, Sara I. Pai, Robert I. Haddad, Maura L. Gillison, Marshall R. Posner; Johns Hopkins Bloomberg School of Public Health, Baltimore, MD; Oregon Health & Science University, Portland, OR; The Johns Hopkins University, School of Medicine, Baltimore, MD; Dana-Farber Cancer Institute/Harvard Medical School, Boston, MA; The Ohio State University, Columbus, OH; Mount Sinai Medical Center, New York, NY
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