Risk-Based Thinking: The Success of Risk-Based Monitoring Begins with...

Toronto, Kanada (PRESSEBOX) 10. Juli 2013

Risikobasierte denken beginnt mit der richtigen Akteure am Tisch zu Fragen — und Antwort – die richtigen Fragen. In diesem kommenden Webinar erlautern Experten aus Quintiles, wie Sicherheit und therapeutische Sanitater, Biostatisticians, Daten-Management-Experten und Operationen-Gurus risikobasierten denken anwenden, bevor ein Prozess beginnt.

Die Lautsprecher pruft auch die zwei Arten von Risiken in der risikobasierten monitoring – wissenschaftliche Risikobewertung und operationelle Risiken, hervorheben:
Wirksamkeit und wissenschaftliche Ergebnisse Patientensicherheit/Wege und Patienten Risiko Verhalten und Daten-Integritat-Risiko

Die Gestaltung und Einrichtung von Warnungen und Triggern gegen verschiedene Parameter der Datenintegritat, Wirksamkeit und operative Durchfuhrung werden auch diskutiert werden. Mit diesen Erkenntnissen werden Benutzer in der Lage zu sehen, wie sie durchfuhren und Aktivitaten zum Schutz gegen Risiken wahrend einer Studie, die Verbesserung von Produktivitat und Effizienz, wobei die Verbesserung der Patientensicherheit und Qualitat zu studieren.

Um mehr uber die Veranstaltung zu erfahren, besuchen Sie http://xtalks.com/Risk-based-Thinking-and-Risk-Monitoring.ashx.

Xtalks, powered by Waben Worldwide Inc., ist ein fuhrender Anbieter von weiterbildende Webinare fur die globale Gemeinschaft der Biowissenschaften. Wenden Sie jedes Jahr Tausende von Branchenspezialist sich an Xtalks fur den Zugang zu qualitativ hochwertigen Inhalten. Xtalks hilft Biowissenschaftler mit Industrie-Entwicklungen, Trends und Vorschriften dem Laufenden zu bleiben. Xtalks Webinare bieten auch Perspektiven auf Schlusselthemen aus Top-Branchen dachte Fuhrer und Dienstleister.

Besuchen Sie fur weitere Informationen uber Xtalks, http://xtalks.com/ContactUs.ashx

Kontakt:
Karen Lim (416) 977-6555 Ext 227
ClientServices (at) Xtalks Punkt () com

View the original article here

Mini-Movies May Boost IVF Success

Mini-movies of growing embryos could help boost the success of in vitro fertilization, a new study found. But the number of women who could benefit from the time-lapse technology is unclear.

For the study, British researchers used time-lapse photography to track the earliest stage of embryonic development – a process that unfolds in womb-mimicking incubators for couples using IVF. The researchers then used an algorithm to spot the embryos most likely to grow into babies.

"Embryo selection based predominantly on specific time-lapse derived algorithms could rapidly become routine in IVF treatment," the study authors wrote in the journal Reproductive BioMedicine Online, describing how the healthiest-looking embryos had a 72.7 percent chance of leading to a pregnancy and a 61.1 percent chance of resulting in a live birth.

Embryos deemed to look less healthy by the time-lapse technique had a 25.5 percent chance of leading to a pregnancy and 19.2 percent of resulting in a live birth, according to the study.

But the study was small, with only 69 couples, and some experts say many women lack the luxury of choice when it comes to embryo implantation.

"A lot of the time, we don't have that many embryos to choose from," said Dr. James Goldfarb, director of the University Hospitals Fertility Center in Cleveland and past president of the Society for Assisted Reproductive Technologies, who was not involved in the study.

An IVF cycle starts with a woman taking drugs to stimulate the production of multiple eggs. After about two weeks, the eggs are collected and fertilized. Then, the resulting embryos are grown in a lab for up to five days, depending on how many there are and how healthy they look.

The more healthy embryos there are, the more likely an embryologist will watch them for five days to let the weakest die off, leaving the strongest behind. The pregnancy rate for women under 35 with day 5 embryo transfers is 69 percent, compared to 57 percent for women with day 3 transfers, according to data from the Cleveland Clinic's IVF Laboratory.

"For some patients, you might get 15 eggs, and maybe 13 will fertilize and you have enough embryos that look good on day 3 to go out to day 5 without a problem," said Goldfarb. "But at the other end of spectrum, you might have a patient with only six or seven eggs, only three or four get fertilized, and by day 3, you only have two that look reasonable."

In that case, Goldfarb added, "it's better to transfer them on day 3."

The number of embryos transferred depends on the woman's age. But for women 35 and under, it's typically one or two, according to Goldfarb. So if only one or two embryos are thriving on implantation day, there's not much of a choice.

But the new study raises an interesting possibility for women with multiple embryos to choose from. Based on time-lapse imaging, the researchers were able to weed out embryos with an abnormal number of chromosomes – embryos that would likely fail to implant in the womb or result in a miscarriage. None of the embryos deemed the least healthy by the time-lapse technique resulted in a pregnancy or a live birth, according to the study.

"In some ways, it's more of a negative to get pregnant and miscarry," said Goldfarb. "That rollercoaster can be much more traumatic than not getting pregnant at all."

You are using an outdated version of Internet Explorer. Please click here to upgrade your browser in order to comment.

View the original article here